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Pim-1 kinase inhibitor 8
CAS No. 916038-47-6
Pim-1 kinase inhibitor 8( —— )
Catalog No. M37329 CAS No. 916038-47-6
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 87 | In Stock |
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| 5MG | 132 | In Stock |
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| 10MG | 211 | In Stock |
|
| 25MG | 411 | In Stock |
|
| 50MG | 661 | In Stock |
|
| 100MG | 1017 | In Stock |
|
| 500MG | 2061 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePim-1 kinase inhibitor 8
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NoteResearch use only, not for human use.
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Brief DescriptionPim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.
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DescriptionPim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM. Pim-1 kinase inhibitor 8 has potent cytotoxicity against MCF-7 and HepG2 cells with IC50s of 0.5 and 5.27 μM, respectively. Pim-1 kinase inhibitor 8 can used in study breast cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC | Pim
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Research Area——
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Indication——
Chemical Information
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CAS Number916038-47-6
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Formula Weight275.3
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Molecular FormulaC14H17N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (454.05 mM; Ultrasonic )
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SMILESN#CC1=C(N=C(C=C1C)C)OCC(=O)N2CCOCC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shaban SM, et al. Design and Synthesis of Novel Pyridine-Based Compounds as Potential PIM-1 Kinase Inhibitors, Apoptosis, and Autophagy Inducers Targeting MCF-7 Cell Lines: In Vitro and In Vivo Studies. ACS Omega. 2023 Nov 27;8(49):46922-46933.?
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